Question: How can I assign a value to an expression?

I want to compute some matrix multiplications and i need this expression to be 1 always, i.e,

x^2+y^2+z^2+w^2=1

for every calculation I do.

I have tried x^2+y^2+z^2+w^2:=1 and assign(x^2+y^2+z^2+w^2,1) but it doesn't work.

What I should type to make it work?

 

Thank you

 

 

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