Question: How can I evaluate a matrix?

I have this matrix

 

uA := Matrix([[-w^2+x^2+y^2-z^2, -2*(w*y+x*z), 2*(-w*x+y*z)], [2*(-w*y+x*z), w^2+x^2-y^2-z^2, -2*(w*z+x*y)], [2*(w*x+y*z), 2*(-w*z+x*y), -w^2+x^2-y^2+z^2]])

and I would like to evaluate the variables like this

 

x = -x, y = -y, z = -z, w = -w

I tried this

Eval(uA, x = -x, y = -y, z = -z, w = -w)

but it didnt work.

 

Any suggestions??

 

Thank you so much

 

 

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