Question: "Warning, solutions may have been lost"

Why can I only get the solution  -(-y + 2 x) ^3  (y + 2 x)  from 2) and not from 1).

I am doing the same thing in both of them but from 1) I get "Warning, solutions may have been lost" when Itry to solve for _F1

I want to go from A-B-C with commands (as in 1) ) without having to retype the expression

1)restart;

diff(F(x,y),x)*(x+ y)+diff(F(x,y),y)*(4*x + y);
                      
pdsolve(%);
             
subs(F(x,y)=1,%);
                     
solve(%,_F1);

Warning, solutions may have been lost


2) restart;

F(x,y)=_F1*(1/((y-2*x)^3*(y+2*x)));
                   
subs(F(x,y)=1,%);
                      
solve(%,_F1);

 Output         -(-y + 2 x) ^3  (y + 2 x)

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